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fall within the confidence intervals of previous estimations by Winterton et al., [6] ...

the two most commonly used relaxed clock models and discuss the evolution of ......

We describe how it can be used to estimate phylogenies and divergence times in the face of uncertainty in evolutionary rates and calibration times.

Our approach also provides a means for measuring the clocklikeness of datasets and comparing this measure between different genes and phylogenies.

The timing of land plant evolution is fundamental to the interpretation of earth history and macroevolution throughout the Phanerozoic.

From these we conclude that our method is phylogenetically more accurate and precise than the traditional unrooted model while adding the ability to infer a timescale to evolution.We attached a prior probability to each fossil-based minimum age, and explored the effects of relying on the first appearance of tricolpate pollen grains as a lower bound for the age of eudicots.Many of our divergence-time estimates for major clades coincide well with both the known fossil record and with previous estimates.With the age of one or several nodes of the tree being known from reference fossils, the relative age estimates induce absolute age estimates and confidence intervals of the nodes of the tree.The MPL method relies on the assumptions that substitutions occur randomly and independently in different sites in the DNA sequence and that the substitution rates are approximately constant in time, i.e., assuming a molecular clock.




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