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While there have been many breakthroughs throughout history in these subjects, the progress has been at times, slow.Advancing technologies have made studying biological phenomena easier as time progresses.Because this was essentially a coding problem, the correlation between nucleic acid bases and the corresponding amino acid in the protein was named the ‘genetic code’.The field of molecular biology can be said to have developed largely as a result of the dedicated work that went into elucidating this code.Gamow envisaged the cavities for amino acid insertion as being diamond-shaped, bounded by a base at each of the four corners.If we consider the helix to be vertically oriented, then the left and right corners of the diamond comprise a complementary base pair – either adenine (A) and thymine (T), or guanine (G) and cytosine (C).

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This landmark discovery immediately raised the question as to how DNA, which constitutes the gene, is able to direct the production of proteins: that is, how information stored in nucleic acid is expressed as information contained in proteins.A series of codons in part of a messenger RNA (m RNA) molecule.Each codon consists of three nucleotides, usually corresponding to a single amino acid. This m RNA molecule will instruct a ribosome to synthesize a protein according to this code.The nucleotides are abbreviated with the letters A, U, G and C. The genetic code is the set of rules by which information encoded within genetic material (DNA or m RNA sequences) is translated into proteins by living cells.Translation is accomplished by the ribosome, which links amino acids in an order specified by m RNA, using transfer RNA (t RNA) molecules to carry amino acids and to read the m RNA three nucleotides at a time.




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